ADDICTION RECOVERY QUOTES

The documentary Russell Brand: Addiction to Recovery resulted in an immediate boost in donations and inspired the managing director of Bury St Edmunds based Chevington Finance and Leasing to offer the charity £106,000 over three years.

They have devised a vaccine that floods the body with an antibody to assault nicotine entering the body.

A study in mice, published in Science Translational Medicine, showed levels of the chemical in the brain were reduced by 85% after vaccination.

Years of research are still needed before it could be tested on people.

However, lead researcher Prof Ronald Crystal is convinced there will be benefits.

"As far as we can see, the best way to treat chronic nicotine addiction from smoking is to have these Pacman-like antibodies on patrol, clearing the blood as needed before nicotine can have any biological effect."

New approach

Other "smoking vaccines" have been developed that train the immune system to produce antibodies that bind to nicotine - it is the same method used to vaccinate against diseases. The challenge has been to produce enough antibodies to stop the drug entering the brain and delivering its pleasurable hit.

Scientists at Weill Cornell Medical College have used a completely different approach, a gene-therapy vaccine, which they say is more promising.

A genetically modified virus containing the instructions for making nicotine antibodies is used to infect the liver. This turns the organ into a factory producing the antibodies.

The research team compared the amount of nicotine in the brains of normal mice with those that had been immunised. After being injected with nicotine, the vaccinated mice had nicotine levels 85% lower.

It is not known if this could be repeated in humans or if this level of reduction would be enough to help people quit.

Prof Crystal said that if such a vaccine could be developed then people "will know if they start smoking again, they will receive no pleasure from it due to the nicotine vaccine, and that can help them kick the habit".

He added: "We are very hopeful that this kind of vaccine strategy can finally help the millions of smokers who have tried to stop, exhausting all the methods on the market today, but find their nicotine addiction to be strong enough to overcome these current approaches."

'Impressive and intriguing'

There are also issues around the safety of gene therapy in humans that will need to be answered.

Professor of genetics at the University of Kent, Darren Griffin, said the findings were "impressive and intriguing with great potential" but cautioned there were still many issues which needed addressing.

He said the main issue "is whether the observed biochemical effects in lab mice genuinely translate to a reduced addiction in humans given that such addictions can be both physical and psychological".

Dr Simon Waddington, from University College London, said: "The technology underpinning gene therapy is improving all the time and it is encouraging to see these preliminary results that indicate it could be used to address nicotine addiction, which is damaging to the nation's health and a drain on the health service economy."

If such a vaccine was developed it could also raise ethical questions about vaccinating people, possibly in childhood, before they even started smoking.

Coca-Cola and Pepsi contain minute traces of alcohol, scientific research published in France has revealed. The revelation will cause concern among those who chose the carbonated soft drink for religious, health or safety reasons. According to tests carried out by the Paris-based National Institute of Consumption (INC) more than half of leading colas contain the traces of alcohol. Can't beat the real thing: The revelation will cause concern among those who chose the carbonated soft drink for religious, health or safety reasons These include the brand leaders Coca-Cola and Pepsi Cola, while it is mainly only cheap supermarket versions of the drink which are alcohol-free. ‘60 Million Consumers’, the French magazine, publishes the results of the tests in its latest issue. They suggest that the alcohol levels are as low as 10mg in every litre, and this works out at around 0.001 per cent alcohol.

Unemployed people suspected of suffering from alcoholism or drug addiction will have their benefits cut if they refuse treatment for their condition, the work and pensions secretary, Iain Duncan Smith, will signal on Wednesday. In a sign of the government's new benefits regime, which lies at the heart of Duncan Smith's cost-cutting welfare changes, staff in Jobcentre Plus offices will be encouraged to cut the jobseeker's allowance of claimants who reject treatment for addiction. The new rules will come into place in October 2013 when the universal credit, which is designed to wrap benefits into one payment, is introduced. A new claimant contract lies at the heart of the universal credit reforms. Claimants will have to sign a contract in which they agree to look for work in exchange for an undertaking from the government to support them while they do so. Government sources said the contract would allow Jobcentre Plus staff to say that a suspected addict is in breach of their commitments if they refuse help for alcoholism or drug addiction. Duncan Smith will give a flavour of the new rules when he addresses an event in parliament organised by Alcoholics Anonymous (AA). He will say: "The outdated benefits system fails to get people off drugs and put their lives on track. We have started changing how addicts are supported, but we must go further to actively take on the devastation that drugs and alcohol can cause. "Under universal credit we want to do more to encourage and support claimants into rehabilitation for addiction and starting them on the road to recovery and eventually work. Getting people into work and encouraging independence is our ultimate goal. Universal credit will put people on a journey towards a sustainable recovery so they are better placed to look for work in future and we will be outlining our plans shortly." It is understood that the work and pensions secretary will not make a formal announcement on Wednesday of the powers that will be handed to Jobcentre Plus staff. Duncan Smith wants to use the event to focus on what he regards as the positive work AA does in helping to treat alcoholism. A government source said: "Iain wants to focus on the brilliant work Alcoholics Anonymous does in changing people's lives. He really wants to encourage people who have drink problems to go to AA for treatment. It will transform their lives and will help them into work." The source said Duncan Smith believes it is right to give jobcentre staff powers to cut benefits if an addict refuses treatment because they can detect signs of trouble. The source said: "The universal credit will allow staff in Jobcentre Plus offices to say: this person has been unemployed for some time. The staff know if people are addicted to alcohol. They know the people they are dealing with. "But we want this to be positive and to be about signposting people to superb organisations that can help them. This is about changing their lives. It is very important to support addicts into the workplace." But if claimants refuse they will have their benefits docked. "There will be sanctions," the source said, citing cuts to the jobseeker's allowance as an example. Ministers believe that one indicator Jobcentre Plus staff can use to see whether a claimant is an addict is the amount of times they apply for a crisis loan. "If you are applying for that up to 10 times a year then that is a sign of a chaotic life," one source said. Analysis by the Department of Work and Pensions shows that almost 40,000 people claim incapacity benefit with alcoholism declared as their "primary diagnosis". Of these, 13,500 have been claiming for a decade or more. There are about 160,000 "dependent drinkers" in England who receive one or more of the main benefits. There are 1m violent crimes a year that are related to alcoholism and 1.2m admissions to hospitals a year related to alcoholism. Universal credit is the most important element of Duncan Smith's welfare reforms, developed during his years in opposition through his Centre for Social Justice, which is designed to achieve his central goal of encouraging people into work. It will integrate tax credits and out-of-work benefits into one payment, with the aim of smoothing the transition to work. Labour has given the universal credit a cautious welcome, though it has taken issue with the scale of benefit cuts. Lord Low of Dalston, the vice-president of the Royal National Institute of Blind People who sits as a crossbencher, told peers this year: "Though it has some very sensible and progressive things at its core, in the shape of the universal credit, nevertheless it goes too far to most people's consciences in the way in which it takes vital support away from some of the most needy in our society."

Eight American soldiers died of overdoses involving heroin, morphine or other opiates during deployments in Afghanistan in 2010 and 2011, according to U.S. Army investigative reports. The overdoses were revealed in documents detailing how the Army investigated a total of 56 soldiers, including the eight who fell victim to overdoses, on suspicion of possessing, using or distributing heroin and other opiates. At the same time, heroin use apparently is on the rise in the Army overall, as military statistics show that the number of soldiers testing positive for heroin has grown from 10 instances in fiscal year 2002 to 116 in fiscal year 2010. Army officials didn't respond to repeated requests for comment on Saturday. But records from the service's Criminal Investigation Command, obtained by the conservative legal group Judicial Watch, provided glimpses into how soldiers bought drugs from Afghan juveniles, an Afghan interpreter and in one case, an employee of a Defense Department contractor, who was eventually fired. The drug use is occurring in a country that is estimated to supply more than 90% of the world's opium, and the Taliban insurgency is believed to be stockpiling the drug to finance their activities, according to a 2009 U.N. study. While the records show some soldiers using heroin, much of the opiate abuse by U.S. soldiers in Afghanistan involves prescription drugs such Percocet, the Army documents show. Judicial Watch obtained the documents under the Freedom of Information of Act and provided them to CNN. Spokesman Col. Gary Kolb of the International Security Assistance Force, the NATO-led command in Afghanistan, verified the documents to CNN on Saturday. One fatal overdose occurred in June 2010 at Forward Operating Base Blessing, after a soldier asked another soldier to buy black tar opium from a local Afghan outside the base's entry control point. The first soldier died after consuming the opium like chewing tobacco and smoking pieces of it in a cigarette, the documents show. The reports even show soldier lingo for the drug -- calling it "Afghani dip" in one case where three soldiers were accused of using the opiate, the Army investigative reports show. The United States has 89,000 troops in Afghanistan. The U.S. death toll since the September 11, 2001, attacks that triggered the war has risen to more than 1,850, including 82 this year, according to the U.S. Department of Defense and U.S. Central Command. Tom Fitton, president of Judicial Watch, said his group was interested in soldiers' drug use partly because the risk was present during the Vietnam War. "You never want to see news of soldiers dying of drug use in Afghanistan," Fitton said. "Our concern is, will the military treat this as the problem that it is, and are the families of the soldiers aware of the added risk in this drug-infested country? "There is a dotted line between the uses. Prescription abuse can easily veer into heroin drug use," Fitton added. "Afghanistan is the capital of this opiate production and the temptation is great there and the opportunity for drug use all the more." The group is concerned that "there hasn't been enough public discussion, and we would encourage the leadership to discuss or talk about this issue more openly," Fitton said. In one case, a soldier bought heroin and the anti-anxiety drug Xanax from five "local national juveniles at multiple locations on Camp Phoenix, Afghanistan, and consumed them," one report states. Soldiers also distributed heroin, Percocet and other drugs among themselves, according to the reports. Another soldier fatally overdosed in December 2010 after taking several drugs, including morphine and codeine, though the drugs were not prescribed for him, the Army documents show. One female soldier broke into the Brigade Medical Supply Office at Forward Operating Base Shank and stole expired prescription narcotics including morphine, Percocet, Valium, fentanyl and lorazepam, the documents show. The investigative reports show soldiers using other drugs, including steroids and marijuana, and even hashish that was sold to U.S. servicemen by the Afghan National Army and Afghan National Police personnel, the reports state.

Sales of the two most popular prescription painkillers in the United States have exploded in new parts of the country, an Associated Press analysis shows, worrying experts who say the push to relieve patients' suffering is spawning an addiction epidemic. Drug Enforcement Administration figures show dramatic rises between 2000 and 2010 in the distribution of oxycodone, the key ingredient in OxyContin, Percocet and Percodan. Some places saw sales increase sixteenfold. Meanwhile, the distribution of hydrocodone, the key ingredient in Vicodin, Norco and Lortab, is rising in Appalachia, the original epicenter of the U.S. painkiller epidemic, as well as in the Midwest. The increases have coincided with a wave of overdose deaths, pharmacy robberies and other problems in New Mexico, Nevada, Utah, Florida and other states. Opioid pain relievers, the category that includes oxycodone and hydrocodone, caused 14,800 overdose deaths in 2008 alone, and the death toll is rising, the Centers for Disease Control and Prevention says. Across the U.S., pharmacies received and ultimately dispensed the equivalent of 69 tons of pure oxycodone and 42 tons of pure hydrocodone in 2010, the last year for which statistics are available. That's enough to give 40 5-mg Percocets and 24 5-mg Vicodins to every person in the United States. The DEA data records shipments from distributors to pharmacies, hospitals, practitioners and teaching institutions. The drugs are eventually dispensed and sold to patients, but the DEA does not keep track of how much individual patients receive. The increase is partly due to the aging U.S. population with pain issues and a greater willingness by doctors to treat pain, said Gregory Bunt, medical director at New York's Daytop Village chain of drug treatment clinics. Sales are also being driven by addiction, as users become physically dependent on painkillers and begin "doctor shopping" to keep the prescriptions coming, he said. "Prescription medications can provide enormous health and quality-of-life benefits to patients," Gil Kerlikowske, the U.S. drug czar, told Congress in March. "However, we all now recognize that these drugs can be just as dangerous and deadly as illicit substances when misused or abused." Opioids like hydrocodone and oxycodone can release intense feelings of well-being. Some abusers swallow the pills; others crush them, then smoke, snort or inject the powder. Unlike most street drugs, the problem has its roots in two disparate parts of the country -- Appalachia and affluent suburbs, said Pete Jackson, president of Advocates for the Reform of Prescription Opioids. "Now it's spreading from those two poles," Jackson said. A few areas that include military bases or Veterans Affairs hospitals have seen large increases in painkiller use because of soldier patients injured in the Middle East, law enforcement officials say. Experts worry painkiller sales are spreading quickly in areas where there are few clinics to treat people who get hooked, Bunt said. In Utica, New York, Patricia Reynolds has struggled to find treatment after becoming dependent on hydrocodone pills originally prescribed for a broken tailbone. The nearest clinics offering Suboxone, an anti-addiction drug, are an hour's drive away in Cooperstown or Syracuse. And those programs are full and are not accepting new patients, she said. "You can't have one clinic like that in the whole area," Reynolds said. "It's a really sad epidemic. I want people to start talking about it instead of pretending it's not a problem and hiding."

CONVICTED drug smuggler Schapelle Corby last night said she was "too scared to get my hopes up" after Indonesia's Justice and Human Rights Ministry recommended her jail sentence be slashed by 10 years - meaning she could be back in Australia within weeks. Her family is now anxiously awaiting a decision by Indonesian President Susilo Bambang Yudhoyono, who will have the final say on whether Corby is released. From her cell at Bali's Kerobokan prison, Corby last night said she was waiting for more information about the ministry's recommendation. Her sister Mercedes, who was visiting Schapelle when the news broke, said that if Dr Yudhoyono did agree to cut 10 years from Corby's sentence, she would be eligible to go home immediately. "She will have done eight years in October, plus she's had two years reduced in good behaviour, so that's 10 years," she said. "So if another 10 years is cut, she should be pretty much eligible for release immediately." Mercedes said, if released, her sister planned to head straight back to Australia to live with her mother Rosleigh in Queensland. Corby was jailed for 20 years in 2004 for attempting to smuggle 4.1kg of marijuana into Bali in a body board bag. The announcement of the major breakthrough in the former Gold Coast beautician's drug saga came as a "pleasant shock" to Corby and her family yesterday when The Daily Telegraph told them of the ministry's recommendation. Mercedes was at the prison having a small birthday celebration with Schapelle for their younger sister Mele, who had just turned 22. "Oh wow, have they recommended clemency? I hope this is true. I better make some calls," she said. A few hours later Mercedes said the family was "too nervous" to get their hopes up and would await the President's ruling before they celebrated. Corby first launched her bid for clemency two years ago, appealing for an early release on the grounds she was suffering from mental illness which could endanger her life. "She's on anti-psychotics to keep her stable, but she goes up and down," Mercedes said. A Justice Ministry official yesterday revealed the recommendation to slash Corby's sentence was based on humanitarian grounds: "Our office agreed with her clemency. We recommended granting it." Corby's lawyer Iskander Nawing described it as a "huge development" and a breakthrough. The recommendation also includes an approval for clemency from the director-general of prisons. Dr Yudhoyono's decision will be based on the recommendation from the Justice Ministry, as well as advice from the Attorney-General's Department, Foreign Ministry and National Narcotics Board. Print

Drug paraphernalia and a white powdery substance were discovered in Whitney Houston's hotel room on the day she died, according to a coroner. The full report says the 48-year-old was found on 11 February lying face down in an overflowing hotel bathtub. Investigators said they recovered a rolled-up piece of paper, a small spoon and a portable mirror in the bathroom. The autopsy concluded that the singer had drowned due to the effects of cocaine use and heart disease. The report also indicated the singer had a perforated nose, a sign of long-term substance abuse. The 42-page document gave more details than an initial report released last month. Houston was found dead hours before she was due to attend a pre-Grammy party. One of the world's best known singers in the 1980s and 1990s, Houston had a long battle with drug addiction. Friends and family have said she appeared committed to a comeback, including a new film, during the time before her death.

Airlines have warned the Home Secretary that Britain "risks gridlock" at airports including Heathrow and Gatwick over the Easter break due to staff shortages. More than 370,000 passengers will leave Heathrow airport between Good Friday and Easter Monday, and 200,000 will pass through Gatwick. A spokesman for Heathrow owner BAA told the Daily Telegraph: "Immigration waiting times during peak periods at Heathrow are currently unacceptable and we have called on the UK Border Force to address the problem as a matter of urgency. "There isn't a trade-off between strong border security and a good passenger experience. UK Border Force should be delivering both." Meanwhile, Britons attempting to travel by rail and road face delays because of engineering works taking place on motorways and train lines. Stretches of the M1 and M25 will be affected, and the seven million passengers travelling by train over the weekend will see disruption to travel to and from Euston, King's Cross, Liverpool Street, and Waterloo stations in London. British Airways and Virgin Airlines are among 11 firms that have written to Theresa May in anticipation of "unacceptable" delays to hundreds of thousands of passengers travelling over the long weekend. The UK Border Agency is under fire for a lack of staff able to carry out full security checks, which the airlines say must result in a recruitment drive or the relaxing of some of the more stringent measures currently in place. A spokeswoman for Virgin Airlines said: "While the decision on what level of check should be made at the border is, of course, a matter for Government, we are concerned that there is currently a mismatch between policy and resource. "After years of reducing frontline staff, returning to a 100% check system will undoubtedly mean lengthy queues at UK airports over critical holiday periods such as Easter and the Diamond Jubilee."

U.S. Food and Drug Administration issued new safety information about these cholesterol-lowering drugs that are prescribed to millions of Americans to lower the risk of heart disease. If you're among them, you should understand what the FDA's new guidance means for your health. "Before anyone gets too concerned, you should know that statins are so widely used because they have a long track record of safety and effectiveness," says Dr. Mark Taber, a cardiologist with SSM Heart Institute at St. Joseph Health Center. "All in all, statins have a very high benefit to risk ratio. The widespread use of the drugs, when indicated, probably accounts to a significant degree for the improvement in life expectancy in this country." The FDA called attention to the threat of liver damage as a rare side effect of statins and advised that regular liver enzyme testing is no longer considered useful in predicting or preventing liver injury. "Actually, in general they liberalized the follow up needed for liver function tests on patients taking statins, due to the very low incidence of true liver issues," Taber says. The main warnings related to a slightly higher incidence of developing diabetes while on statins, and a poorly substantiated claim that statins could result in cognitive impairment. Taber points out that cognitive problems, such as confusion or memory problems, were not documented in clinical studies, only by patient reports to the FDA website. "By stating these concerns, the FDA is raising awareness about the potential side effects of statins, but cardiologists already know that there are inherent risks, and we monitor patients appropriately to help ensure that side effects do not occur or are dealt with quickly," Taber notes. "If there is any evidence of a side effect that could be problematic, we can change the medication. But the fact remains that it's important to decrease risk of heart disease, and for many people statins are needed when diet and exercise alone don't result in acceptable cholesterol levels." Whenever a new prescription medication is started, you should look over the package insert to learn about potential side effects. Signs of liver damage, for instance, include fatigue, loss of appetite, right upper abdominal pain, dark urine and jaundice. Any of these symptoms should be reported to your doctor for evaluation. It is important to remember that you should not stop taking a medication without consulting your doctor first. Discontinuing use of a prescribed drug can be far more dangerous than the side effect you're worried about. "All the side effects listed by the FDA are rare, and the risk of heart attack is far more concerning," Taber says. "Some patients may need extra monitoring or may need to try more than one statin before we find the optimal choice, but in general statins are very well tolerated and don't cause problems for the people who take them." The advice above is universal when it comes to your health. Concerns should be discussed with your doctor, and decisions should always be made as part of a team approach to creating a healthy life.