ADDICTION RECOVERY QUOTES

John Holliday had been on a higher 40mg dose of cholesterol pills for only a few weeks when he started to lose his concentration. ‘I’d be watching TV and suddenly find myself unable to follow the plot of a drama,’ says John, 52, a telecoms project manager who lives in Southend-on-Sea, Essex, with his wife Jill, 51, and their two children Adam, 20, and Emma, 16. ‘I’d have to read the same page of a book over and over because I couldn’t take any information in. ‘I’d always been known for my amazing memory — I was great on trivia and had total recall of events that happened 20 years ago, but suddenly I couldn’t remember things and my brain felt fuzzy.’ Just like up to seven million other people in Britain, John had been prescribed a statin to lower his blood cholesterol levels. The drugs are credited by the British Heart Foundation as contributing towards the dramatic 50 per cent fall in deaths from heart attacks in the past ten years. But while there is consensus that statins are lifesavers for people who have previously had a heart attack, concern is growing over their debilitating side-effects. They include muscle weakness, depression, sleep disturbance, sexual dysfunction, muscle pain and damage, gastro-intestinal problems, headaches, joint pains and nausea. Now, official bodies here and in the U.S. have ordered that the drugs must carry warnings for cognitive problems, too. Worryingly, it’s claimed GPs are failing to warn patients of the effect statins can have on the mind — meaning they may mistake them for signs of ageing or Alzheimer’s. ‘When I went back to my doctor after six weeks for a blood test, I told him how dreadful I was feeling,’ says John. ‘But he just said all drugs had side-effects and didn’t mention reducing the dose.’ It's claimed GPs are failing to warn patients of the effect statins can have on the mind - meaning they may mistake them for signs of ageing or Alzheimer's Things came to a head when a friend showed John an electrical circuit he’d built for his car. ‘I’d worked with circuits since I was 16 but it made no sense,’ he says. So John insisted on seeing his doctor again and repeated his concerns about his rapidly declining memory. This time the GP told him he could start on another type of statin when he felt well enough, and so John stopped taking the drugs immediately. ‘It took a few months, but gradually my memory returned and I’ve got my concentration back. I can’t say for sure statins caused these problems, but it seems like too much of a coincidence.’ Earlier this year, the Food and Drug Administration (FDA) in the U.S. ordered statins must carry warnings that some users have reported cognitive problems including memory loss, forgetfulness and confusion. This followed a decision by the UK’s Medicines Healthcare Regulatory Agency (MHRA) to add memory problems to the list of  possible statin side-effects in late 2009. The FDA said reports about the symptoms were from across all statin products and age groups. Those affected reported feeling fuzzy or unfocused in their thought process — though these were found to be rare and reversible. The FDA also warned, following U.S. research, that patients on statins had a small excess risk of developing Type 2 diabetes — but stressed that the benefits of taking a statin still outweigh this. The MHRA had 2,675 reports for adverse drug reactions connected with statins between 2007 and 2011. Officially, side-effects are rare —affecting only 1 per cent of people on the pills — but some doctors say they are under-reported. Dr Malcolm Kendrick, a GP and author of The Great Cholesterol Con, says he frequently sees patients suffering from mental confusion in his job in hospital intermediary care for the elderly. ‘Many of the patients I see will have been admitted to hospital after a fall or similar crisis,’ he says. ‘If they appear confused I’ll often advise taking them off statins to see if it has any effect — in my experience, about 10 to 15 per cent of people who appeared to have memory problems experienced an improvement in their memory symptoms after being taken off the drug. ‘I had one dramatic case where a lady was admitted to hospital on 40mg a day of simvastatin with such poor memory function her family asked me about power of attorney. 'I suggested taking her off statins and within a week her memory had returned to normal. She went home a fit and independent 83-year-old.’ Dr Kendrick says cholesterol is the main constituent of synapses (structures that allow signals to pass between brain cells and to create new memories) and is essential for brain function. ‘It is still not proven that statins have a significant effect on mortality — it has been calculated that a man who has had a heart attack who took a statin for five years would extend his life by only 14 days. 'Too many statins are being given to people at low risk. ‘Even in the highest risk group you need to treat 200 people a year with statins to delay just one death. 'One day the harm these drugs are doing is going to be obvious — the benefits are being over-hyped and the risks swept under the carpet.’ While Dr Kendrick’s controversial view is in the minority, one large review of 14 studies by the London School of Hygiene and Tropical Medicine, published by the highly respected Cochrane Library last year, concluded there was ‘little evidence’ cholesterol-lowering drugs protect people who are not at risk of heart disease. This review has been criticised by other doctors who say side-effects are rare and that there are still benefits even for people at lower risk who do not have established heart disease. These defenders of statins include Professor Colin Baigent of the Clinical Trial Service at Oxford University, who published research in 2010 showing statins reduced deaths from all causes by 10 per cent over five years. ‘There is relatively little evidence of cognitive impairment — what evidence there is all comes from observational studies.  ‘People read about side-effects and then put two and two together and blame the statins for their muscle pain or other health problems — it’s just not reliable evidence. ‘If you look at the best-quality randomised controlled trial where patients don’t know if they are taking a statin or placebo, there is no evidence of memory problems. 'Even the FDA says the risks of cognitive problems are very small and go away when statins are discontinued. ‘We’re in danger of forgetting just how effective these drugs are.’ Dr Dermot Neely of the charity Heart UK, and lead consultant at the Lipid and Metabolic Clinic at the Royal Victoria Infirmary in Newcastle, agrees side-effects with statins are rare. ‘I’ve been dealing with patients on statins since 1987 and I can count on the fingers of one hand the number whose memory symptoms turned out to be caused by statins.’ However, he said he often saw patients who had not been told about side-effects. ‘It’s important GPs are clear about the drugs statins can interact with, such as certain antibiotics, as this can get overlooked. ‘If a patient notices an adverse effect after starting statins, they should discuss this with their GP —but not stop their drugs suddenly because this can be dangerous.’ Sonya Porter, 73, decided to stop taking statins after her memory problems became so bad that she walked away from a cashpoint leaving her money behind. ‘I was permanently fuzzy-headed and just couldn’t seem to concentrate,’ says Sonya, a retired PA from Woking, Surrey. Then I started to get scared I might have Alzheimer’s. After reading about memory problems associated with statins, I thought it was at least a possibility. I decided to come off the pills to see if it made any difference. ‘I didn’t ask my GP, I just did it — I’d rather die of a heart attack than Alzheimer’s disease. Within a month I felt normal again and didn’t have any problems with memory. ‘I’m terrified that I could have been misdiagnosed with Alzheimer’s.’ John Holliday is also reluctant to go back on statins. ‘I wouldn’t rule it out completely — my latest test showed my cholesterol levels have gone up,’ he says. ‘But on balance, I’d rather take my chances with heart disease than feel as confused as that again. It’s all very well living slightly longer — but it’s about quality of life, too.’

It was a case of deja vu last night for the long-suffering residents of Salou, the northern Spanish town where thousands of British students flock every spring for four nights of drunken debauchery.

For the twelfth time, the Costa Dorada resort has been overrun by Saloufest, the notorious annual sports tour returning for another round of hard drinking, half-naked partying - and the odd day of volleyball or hockey.

The first pictures released from this year's event paint a familiar picture: packs of fresh-faced revellers in proudly ridiculous fancy dress, their flesh largely bare and arms aloft as they stagger and bellow through the streets.

On the march: British students wrapped in flags as they head out for the first night of parties at SalouFest in Salou, Spain

Fireman's lift: A British student makes off with a fellow reveller as the drunken Saloufest parties spill out on to the streets

Culture clash: Two young women match geisha-style makeup with pink bum bags for a night out in the Costa Dorada resort

The first 5,000 of a total 8,200 people are said to have made the trip from Britain's universities yesterday, marking an increase of 1,000 on last year.

Police say the first night of the tour passed without any arrests being made - but past form suggests they won't be holding out much hope for an easy ride.

Last year's event saw officers launch a crackdown on any students caught drinking in public, putting an end to the days when the locals would turn a blind eye to those flouting Salou's alcohol bylaws.

The town also decided to uphold rules preventing the Saloufest partiers from roaming around town half-naked.

The 2011 tour saw two toga-wearing students hauled off to a police station and fined £265 for breaking the alcohol laws.

This year the local authorities have handed out leaflets warning British visitors not to drink on streets and beaches, while those found stumbling around shirtless can expect to face the consequences.

Riot of colour: There's no missing these Brits abroad as they pull on garish tones and leggings for a debauched night in the Catalan village

Rowdy: Four students holler from the terrace of a nightclub during the first night of booze-soaked parties

Sitting comfortably? A show of bravado sees one British student doing a press-up as another sits on his back

Spanish media reports that ILoveTour, the firm that organises the festival, has some 30 supervisors on hand to babysit the horde of 18-to-23-year-olds.

One account, from Spanish newspaper El Pais, talks of streets streaked with vomit and urine, disoriented youths, deafening noise and riot vans on standby.

Despite local opposition, hoteliers in the area support Saloufest because it extends the holiday season and is timed so as not to interfere with the influx of Easter tourists. 

In an effort to keep the peace, some of the seven hotels set aside for the event have opted to separate their British guests from other holidaymakers.

The basic festival package sees students shell out £189 for coach travel and four nights in two-star accommodation, with optional extras including day trips to nearby Barcelona and Port Aventura.

Shameless: A passerby cheers as two partygoers get up close and personal outside an Irish-themed bar

In the gutter: The week-long tour has barely begun, but Saloufest seems to have taken its toll as these two huddle on the pavement outside a nightclub

Sin city: Dog collars and a novelty cross pass for fancy dress on the streets of Salou

Tribes: Clusters of UK students stagger through the village in fancy dress. A vague cavewoman theme finds this pair draped in animal print

Bookish? A mob of Saloufest drinkers in 'geek' fancy dress, one of the go-to costume themes for student union club nights up and down the UK

 Teenagers as young as 11 are modelling sex acts and rape, in the form of daggering, on the dance floor with their peers. Deputy Children's Commissioner Sue Berelowitz said: "there's not a lot separating that kind of behaviour from actual violent, coercive sex." Footage seen by Channel 4 News [see above] shows an under-18s club night in East London. As with all 'under-18s' club nights, everyone is between 11 and 16. Some of the children look much younger. The club is packed. The music: Caribbean dancehall. The dancing style: daggering. It is a style of dancing that any carnival regular will be used to. Aficionados will no doubt, have a more technical description of the style but it mainly involves women bending over and rubbing their backsides up against the men's crotches. During that August weekend in Notting Hill every adult gives it a go. But what's different about this night club is that every child is giving it a go. Spurred on by the DJ, the 'daggering' becomes more enthusiastic, some of it verging on violent. Boys and girls end up on top of each other on the floor simulating sex. Throughout the night someone employed by the club promoter (presumably an adult) is filming it all and uploading it on the club's website via YouTube.

legal high known as "mexxy" is to be outlawed, the Government has announced. It follows concerns that two people whose bodies were found in Leicestershire in February may have taken some form of the drug after buying it over the internet. Methoxetamine, or mexxy, will initially be made illegal for 12 months while Government advisers decide whether to ban it completely. Crime Prevention Minister Lord Henley said: "Making this drug illegal sends a clear message to users and those making and supplying it that we are stepping up our fight against substances which are dangerous and ruin the lives of victims and their families. "But making drugs illegal is only part of the solution. "It is important for users of these harmful substances to understand that just because they are described as legal highs, it does not mean they are safe or should be seen as a 'safer' alternative to illegal substances." Anyone caught making, supplying or importing the drug faces up to 14 years in prison and an unlimited fine. Under the change in law, police and border officials will also have new powers to search or detain anyone they suspect of having the drug and seize, keep or dispose of a substance they suspect is methoxetamine. After its growing use as a party drug, the Home Office referred mexxy to the Advisory Council on the Misuse of Drugs (ACMD) for its views on controlling it earlier this month. The drug, used as an alternative to ketamine, is widely available on the internet. Its effects include a faster heart rate, hallucinations, hypertension, loss of balance, higher blood pressure, agitation and cardiovascular conditions. Tests by the ACMD also found evidence that use of methoxetamine can lead to "significant additional toxicity". Professor Les Iversen, chairman of the ACMD, said: "The evidence shows that the use of methoxetamine can cause harm to users."

CANNABOOST plant food is one of the best selling products at the Hydroexpress hydroponics store in Stirchley, a working-class part of Birmingham. The small shop, its windows filled with graffiti-style posters, also sells fertilisers with names like “Nirvana” and “Bud Candy”, alongside strong lights and giant rolls of tin foil to line greenhouses. In one corner, a couple of juicy-looking tomato plants grow in a demonstration set-up. But the youth behind the counter guesses that his customers are “not all growing tomatoes”. Birmingham now has 58 hydroponics shops, up from 42 just a year ago. Whether aided by the latest plant-growing technology or not, cannabis production is soaring. According to the Association of Chief Police Officers, the number of cannabis factories detected each year increased from around 800 in 2004 to 7,000 in 2010. Birmingham is one of the most fertile areas; West Midlands Police, which set up a Cannabis Disposal Unit in 2010 to tackle the problem, dismantled more than 500 factories last year. Your correspondent visited one recently closed by police; the gardener was a cocaine-addicted woman growing a few plants in a spare room in the hope of earning a cut. Other set-ups have been found in tents in the bedrooms of high-rise council flats and in the lofts of terraced family houses. Many growers are simply feeding their own habits. As one officer on the West Midlands Police drugs team says, “It’s becoming the most popular cottage industry in the country.” In this section A big splash with little cash Falling flat Earning a hearing The worst job in the world Constituency of the world Mother tongue Money for old metal »Legal high A rock and a hard place The Notting Hill budget Reprints Related topics United Kingdom Birmingham, England Small growers are squeezing out both importers and the well-connected, often Vietnamese, gangs that once dominated domestic production. The big cannabis factories set up by the latter, with their telltale heat hazes, are fairly easy to spot. Smaller operations are often uncovered only when the electric lights start fires, or when local teenagers mount a burglary. The police and the courts can neither keep up with the surge in small-scale production, nor are they desperately keen to do so. Last month the government published new sentencing guidelines that advised judges to treat small cultivators less strictly. Attitudes to smokers are softening, too. The reclassification of cannabis in 2009, from class C to the more stringent class B, was oddly accompanied by a more liberal approach to policing consumption. Users caught on the street are rarely arrested; rather, they are issued “cannabis cautions” (a reprimand which doesn’t appear on a criminal record) or fined. In Brixton, a south London neighbourhood, an open-air cannabis market exists within ten minutes’ walk of the underground station. The dealers are frequently moved on but they soon regroup elsewhere. As one dealer admits, his competitors are a bigger hassle than the police. “They get to fightin’, over money and things,” he says in a deep Caribbean drawl. Violence is far more likely to get a dealer into legal trouble than business. Strangely, this lackadaisical approach is not encouraging people to take up the reefer habit. According to the European Monitoring Centre for Drugs and Drug Addiction, the proportion of people who admit to having used cannabis in Britain has fallen more quickly than in any other European country over the past few years. Just 6.8% of adults told another survey that they used cannabis in 2010, down from 10.9% eight years earlier. The herb is now ubiquitous and effectively tolerated—and, perhaps as a result, not all that alluring.

Russian banker shot five times close to London's financial district had been days away from giving evidence to an investigation into the attempted murder of a former business associate, his lawyer has said. German Gorbuntsov, who at the height of his business empire owned four Russian banks, was walking towards his apartment block near the Canary Wharf banking district when a gunman opened fire on Tuesday evening, leaving him badly injured. London police said on Saturday they were keeping an open mind about the motive of the attack. Gorbuntsov's lawyer, Vadim Vedenin, said the 45-year-old remained in a medically induced coma to give him a chance to recover, and that doctors were hoping to revive him in about three days. Vedenin said his client had been due to give evidence before the end of the month to an investigation by Russian prosecutors into the attempted murder of another Russian banker and former business associate of Gorbuntsov's, Alexander Antonov, in 2009. "He was preparing to give evidence on certain people. He has already given it in written form and he was going to do so in official testimony," Vedenin said by phone on Saturday, adding that Gorbuntsov had come to London because he feared for his life. The attack occurred outside the door of a block of high-end serviced apartments a short walk from the skyscrapers of Canary Wharf. A member of the building's staff, who declined to give his name, said he heard no shots, but ran outside when he heard frantic shouting. "He is a customer here. He was still alive. He spoke to us in Russian. I understood what he was saying," the member of staff, a Polish man, said. "He was swearing a lot." LONDON RUSSIANS London is home to thousands of Russian business people seeking capital, prestige and, in many cases, a haven from the rough and tumble of their home country's financial world. Alexander Antonov made his career in the nuclear industry, then became its banker as owner of Konversbank, a financial institution founded to serve the nuclear industry about two decades ago. Antonov said he and Gorbuntsov had disagreed over the terms of a bank sale just before the debt crisis of 2008, but that there had been no acrimony. "Our relationship is friendly, and it has always been friendly," he told Reuters. "I have a great personal interest in his testimony." The attempt on his life in 2009 was linked in Russia to the 2008 murder in Moscow of Ruslan Yamadayev, a powerful opponent of the Kremlin-backed Chechen leader Ramzan Kadyrov. The two incidents were tried as a single case and three men were convicted. But the person or persons who ordered the murders was never identified, and the case had lain dormant until this year. Diplomatic relations between Russia and Britain have been tested by a series of disputes involving Russian emigres. Russia has refused to extradite the man suspected of murdering former Russian spy Alexander Litvinenko by putting radioactive polonium in his tea in London. Meanwhile London courts have refused to extradite men wanted in Russia, including the Russian tycoon Boris Berezovsky, a former Kremlin insider turned fierce critic with criminal convictions in Russia. Berezovsky, who says the charges brought against him in Russia are politically motivated, said by telephone from London that he did not know Gorbuntsov personally, nor did he know of any Russian criminals hiding out in London. "One can give differing views, but it is important to understand that, from my not-exactly-dilettantish point of view, there is no place safer than London from Kremlin bandits or from Russian or international criminals," he said. "But that of course is no guarantee they won't get you."

More and more footballers are going bankrupt despite Premier League wages now averaging £1.47 million a year, experts have claimed.  Mark Sands, head of bankruptcy at accountancy firm RSM Tenon, said the lavish lifestyles of the players coupled with poor investment choices has led to increased vulnerability. "In 2010 the average salary of a player in the Premier League was £1.47 million, 56 times the average UK wage," Sands told the Birmingham Mail. "But as their wages have increased so have the number who become insolvent. "We have certainly had an increase at RSM Tenon in the past three years. The main reasons for this can be unsustainable consumption, falling incomes after leaving the top flight, poor investment and lack of financial awareness." Last month former England international Lee Hendrie was forced to declare himself bankrupt after racking up debts of more than £200,000 with the taxman, despite earning £24,000 a week at the peak of his career. RSM Tenon stated: "The debts have apparently been a result of a tax scheme Hendrie was advised to enter into which was rejected by HM Revenue & Customs, leaving an unpaid tax bill which led to the petition. “Investments made during his peak years, in properties and film-related partnerships, went bad, leaving no money for Hendrie to turn to when times were tough.” Last year, current Tottenham goalkeeper Brad Friedel was also declared bankrupt after his non-profit US football academy ran up debts of close to £5m.

Sam Faiers and the rest of her TOWIE castmates are apparently jetting off to Spain to film a special this summer. The reality TV stars will be shooting in sunny Marbella - where they holidayed last May - later on this year, reports the Daily Star. Speaking at the Tric Awards, Sam said the special will need "lots of dramas, a fight and maybe a wedding." Co-star Gemma Collins, who was snapped soaking up the rays in a black bikini during last year's trip, said the group are "all up for it". "We've been begging for a summer special in Marbella for a while," she said.

The past month, the spotlight has been on James Ibori, the governor of Nigeria's Delta state from 1999 to 2007, who pleaded guilty at in a London court to 10 counts relating to conspiracy to launder funds from the state he governed. Ibori was accused of siphoning off an estimated $250m and laundering it in London through a number of offshore companies and financial intermediaries to fund his extravagant lifestyle of lavish mansions, expensive cars and private jets. This mode of illicit capital flight is by no means restricted to one rogue Nigerian governor or even African leaders at large, nor is it the most important means by which capital leaves the continent (and developing countries generally) illicitly. True, $250m from one source is substantial. But this pales into insignificance compared with the estimated $100bn that left Nigeria illicitly between 1970 and 2008, according to Global Financial Integrity (GFI). The bulk of this haemorrhage, contrary to popular belief, is not through the laundering of corrupt money but through commercial activities, and particularly through multinational corporations. According to GFI's conservative estimates, more than $1.8 trillion left African shores illicitly between 1970 and 2008. Of this, only 3% is attributable to bribery and theft by government officials, 30%-35% results from the laundering of criminally acquired wealth (drugs, illegal arms sales, human trafficking, etc), and the bulk – 65%-70% – is from commercial activities, especially through trade mis-pricing of goods. Over the last 10 years, the average annual outflows of this sort exceeded $50bn. This compares with annual aid inflows of less than $30bn. The outflows are largely to avoid or evade tax and to conceal wealth. This week's proposed change by the chancellor, George Osborne, on how foreign subsidiaries of multinationals based in the UK are taxed, will give even less incentive to keep money in poorer countries. Reform of these controlled foreign company rules in the upcoming budget would strengthen the financial case for shifting money to tax havens by making profits made by multinationals abroad and retained in offshore jurisdictions free from UK tax. This could cost developing countries £4bn a year in lost tax revenue, according to ActionAid estimates. These outflows undermine the rule of law, stifle trade and worsen macroeconomic conditions. They are facilitated by around 60 tax havens and secrecy jurisdictions that enable the creating and operating of millions of disguised corporations, shell companies, anonymous trust accounts and fake charitable foundations. They allow the likes of Ibori and many multinational corporations to cripple Africa financially and politically. Given that about 50% of global trade passes through tax havens, these jurisdictions facilitate trade mis-pricing by making it difficult for documentation to be traced. Transnational companies have the ability to set up multiple trusts and shell companies in these jurisdictions. This is significant because about 60% of global trade takes place between and within multinational companies. Secrecy also attracts criminal activity, and the laundering of corrupt money through concealment of the natural beneficiaries behind shell companies and trusts. Africa is experiencing economic growth, and for the increasing wealth to be channelled to public services, development and the achievement of the millennium development goals by 2015, it is urgent the problem of tax havens as a conduit for illicit outflows is addressed. The high-level panel set up by the African Union, the African Development Bank and the UN Economic Commission for Africa, and chaired by former South African president Thabo Mbeki, is a significant step forward – and testifies to the importance of this issue for Africa's development. The ball is now in the court of the rich countries.

The pet owners are being targeted in a crack down on those breaking strict bylaws with 440 summonses being issued in just 30 days. The most common offence involved dogs not being kept on leads, while others included owners not clearing up after their animal and dogs not being muzzled. Fines ranged from 75 to 3,000 euros depending on the offence. The most serious breach of the law involved 24 summonses for owning potentially dangerous breeds that weren’t registered or did not have the necessary paperwork.